No! we can not run any simple program with out using any interface such as operatin systen or System software. but in some cases like Machine level languge or firmware run without any software because it directlly communicate with hardware and makes the hardware active so other program can run using his platform.
Siba Ranjan Biswal
Feb 11th, 2014
Yes a program can be executed with out operating system..for example the boot executable program runs in systems while no operating system is available prior to it.